Dr. Nirmal K. Rana's research group aims to design and synthesize new organocatalysts and apply them in developing novel asymmetric methodologies mainly emphasizing on domino/cascade/sequential reactions for creating multiple stereocenters within a molecule. Additional targets are the exploration of dual organo-metal catalysis and biocatalysis. Our other aim is to develop new methodologies using continuous-flow systems using immobilized chiral catalysts for the production of fine chemicals, chiral drug molecules/intermediates with industrial implementation. We are also focused to utilize our methodologies as key steps for the synthesis of architecturally interesting and biologically active molecules.

Dr. Rohan D. Erande’s research group mainly focused on the total synthesis of biologically important Natural Product. We are highly interested in method development like metal catalysis, organocatalysis, Lewis acid catalysis and cascades of reactions to resolve the complexity of targeted natural products in access to achieve their total synthesis in efficient and step- and atom-economical way. An aiming to target potent drug molecules with new mechanisms of action, we are exploring the field of medicinal chemistry by collaboration with bio-laboratories and pharmaceutical companies towards drug discovery and development in India.

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