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Advanced Biosciences & Neuroscience Laboratory
The Advanced Biosciences and Neuroscience laboratory is a part of the center of excellence in biologically inspired systems science (BISS). This laboratory provides cellular and molecular investigative tools for UG and PG teaching and research in neuroscience. Cell culture studies are utilised along with molecular biology, biochemistry and microscopy approaches to elucidate the molecular mechanisms underlying molecular and cellular interactions underlying inflammation and repair. Inflammation is a key component of many diseases including traumatic brain injury, cancer, multiple sclerosis, stroke, asthma, Parkinson’s disease and Alzheimer’s disease. Inflammation is characterized by accumulation and proliferation of innate immune cells. This is followed by clearance of dead cells and cellular debris along with enhanced expression of molecular mediators called cytokines and chemokines, which cause migration and proliferation of immune cells and may even lead to cell death. Understanding the mechanisms by which inflammation occurs, and the molecular mediators involved in this process, is necessary for identification of potential therapeutic targets.




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