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Lecture on "Aggregated Small Molecules: Hydrogel and AIEgens" - 9 March 2018

Date and Venue Information:
09 March 2018, 4:30 PM, Seminar Hall, Chemistry Department

Title of Lecture:
"Aggregated Small Molecules: Hydrogel and AIEgens" by Professor Debapratim Das, Associate Professor, Department of Chemistry, Indian Institute of Technology Guwahati, North Guwahati, Assam, India 781039.

Abstract
“Together we stand – divided we fall”
Self-aggregation of small molecules by non-covalent interactions is an important phenomenon. Molecules aggregated to form self-assembled soft materials which find application in various fields of science. Our group at IIT Guwahati is devoted to understand and develop new soft-materials using this supramolecular approach. This lecture consists two different stories of supramolecular chemistry. The first part of the lecture will be about the design and development of a small peptide based hydrogel capable of sensing pH inside cells and track mitochondria.¹
The second part is about Aggregation Induced Emission (AIE) behavior of Schiff-bases in
aqueous-organic solvent mixtures. Over last two decades, the behavior of these Schiff-bases are misinterpreted and considered as AIE. Surprisingly, the basic text book chemistry is overlooked for years. In a systematic analysis of a series of probes, we have unveiled the underlying mechanism.²
 
References:
1. Biomacromolecules 2017, 18, 3630–3641.
2. J. Phys. Chem. C 2018, 122, 3655–3661.