| Date and Venue Information: | |
| 09 March 2018, 4:30 PM, Seminar Hall, Chemistry Department |
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| Title of Lecture: | |
| "Aggregated Small Molecules: Hydrogel and AIEgens" by Professor Debapratim Das, Associate Professor, Department of Chemistry, Indian Institute of Technology Guwahati, North Guwahati, Assam, India 781039. |
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| Abstract | |
| “Together we stand – divided we fall” | |
| Self-aggregation of small molecules by non-covalent interactions is an important phenomenon. Molecules aggregated to form self-assembled soft materials which find application in various fields of science. Our group at IIT Guwahati is devoted to understand and develop new soft-materials using this supramolecular approach. This lecture consists two different stories of supramolecular chemistry. The first part of the lecture will be about the design and development of a small peptide based hydrogel capable of sensing pH inside cells and track mitochondria.¹ | |
| The second part is about Aggregation Induced Emission (AIE) behavior of Schiff-bases in aqueous-organic solvent mixtures. Over last two decades, the behavior of these Schiff-bases are misinterpreted and considered as AIE. Surprisingly, the basic text book chemistry is overlooked for years. In a systematic analysis of a series of probes, we have unveiled the underlying mechanism.² |
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| References: | |
| 1. Biomacromolecules 2017, 18, 3630–3641. 2. J. Phys. Chem. C 2018, 122, 3655–3661. |
